目的:了解团体辩证行为疗法(dialectical behavior therapy, DBT)治疗伴有非自杀性自伤(non-suicidal self-injury, NSSI)行为的青少年抑郁障碍患者的临床疗效。方法:选择40名伴有NSSI的青少年抑郁障碍患者为研究对象,分为对照组和实验组,对照组应用氟西汀治疗,实验组应用氟西汀联合团体DBT治疗。比较两组患者治疗前、治疗4周后、治疗8周后的汉密尔顿抑郁量表(Hamilton depression scale, HAMD)、认知情绪调节量表(cognitive emotion regulation questionnaire, CERQ)、自我伤害想法和行为访谈表(self-injurious thoughts and behaviors interview, SITBI)的变化。结果:实验组比对照组在认知情绪调节和NSSI方面有更显著的改善(P Objective: To study the clinical efficacy of group dialectical behavior therapy (DBT) in treating adolescent patients with depressive disorders accompanied by non-suicidal self-injury (NSSI). Methods: A total of 40 adolescent patients with depressive disorders accompanied by NSSI were selected as the subjects of the study, divided into a control group and an experimental group. The control group was treated with fluoxetine, while the experimental group received a combination of fluoxetine and group DBT. The changes in the Hamilton depression scale (HAMD), cognitive emotion regulation questionnaire (CERQ), and self-injurious thoughts and behaviors interview (SITBI) before treatment, after 4 weeks of treatment, and after 8 weeks of treatment were compared between the two groups. Results: The experimental group showed more significant improvements in cognitive emotion regulation and NSSI than the control group (P < 0.05). Conclusion: Group DBT can change the cognitive emotion regulation strategies of adolescent patients with depressive disorders accompanied by NSSI, effectively reducing the occurrence of NSSI behaviors and thoughts.